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Preimplantation Genetic Testing (Basics)

Welcome to our guide on Preimplantation Genetic Testing (PGT). If you're considering or undergoing IVF (In Vitro Fertilization), PGT can be an important part of the process. It helps ensure the health of the baby before pregnancy. This guide will explain PGT in simple terms, its types, and what it means for you as a parent.



 

This article is part of our Basics collection! These articles contain only the most important information.



 


This article is pending medical review.

Contributors

Written by Sajjad Biglari

Edited by Juliëtte Gossens

 

What is PGT?

PGT is a test performed on embryos created through IVF. It checks for genetic issues before the embryo is placed in the womb. This testing helps identify embryos with the best chance of developing into a healthy pregnancy.



Types of PGT:

  • PGT-A (Aneuploidy Screening): Checks for the right number of chromosomes.

  • PGT-M (Monogenic/Single Gene Disorders): Looks for specific genetic disorders.

  • PGT-SR (Structural Rearrangements): Tests for chromosomal structure issues.


The PGT Process Explained: 


  1. IVF is done to create embryos.

  2. A few cells are taken from each embryo.

  3. These cells are tested for genetic issues.

  4. Healthy embryos are chosen for pregnancy.


Benefits and Limitations of PGT

  • Benefits: Increases the chance of a healthy pregnancy, reduces the risk of certain genetic disorders.

  • Limitations: Not all genetic issues can be detected, and the process requires IVF.


Ethical Considerations

PGT raises important ethical questions. It's about balancing the desire for a healthy baby with concerns about selecting embryos based on genetic information. We encourage you to discuss these aspects with your healthcare provider.


FAQs for Parents:


  • Q: Is PGT safe for the embryo? A: Yes, PGT is a common procedure and is generally considered safe.

  • Q: Can PGT guarantee a healthy baby? A: While PGT increases the chances of a healthy baby, it cannot guarantee it.


 

For sources supporting the information in this article, please head to our in-depth article on the topic via the button at the top of the article.


Please note: the information we provide to you here is for educational purposes only. If you’re experiencing any discomfort or have any complaints or questions about your health, please contact your doctor or other relevant health professional. We don’t provide medical advice.

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